4.831 Impact Factor. Once production of your article has started, you can track the status of your article via Track Your Accepted Article. Submit your article. Help expand a public dataset of research that support the SDGs. HZ-A-005, a potent, selective, and covalent Bruton’s tyrosine kinase inhibitor in preclinical development, Design, synthesis and biological assessment of acridine derivatives containing 1,3,4-thiadiazole moiety as novel selective acetylcholinesterase inhibitors, Synthesis, anticancer and antioxidant properties of new indole and pyranoindole derivatives, Macrocyclic diterpenoids from the seeds of Euphorbia peplus with potential activity in inducing lysosomal biogenesis, Design and synthesis of novel isatin-based derivatives targeting cell cycle checkpoint pathways as potential anticancer agents, Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors, Neurotrophic and anti-neuroinflammatory constituents from the aerial parts of Coriandrum sativum, Targeted degradation of CD147 proteins in melanoma, Cytotoxic secondary metabolites from the vulnerable conifer Cephalotaxus oliveri and its associated endophytic fungus Alternaria alternate Y-4-2, Design, synthesis and antitumor activity of icotinib derivatives, Synthesis, biological properties, and acid dissociation constant of novel naphthoquinone–triazole hybrids, Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity, Hydroxamic acid with benzenesulfonamide: An effective scaffold for the development of broad-spectrum metallo-β-lactamase inhibitors, An allomaltol derivative triggers distinct death pathways in luminal a and triple-negative breast cancer subtypes, Synthesis of novel halogenated triarylpyrazoles as selective COX-2 inhibitors: Anti-inflammatory activity, histopatholgical profile and in-silico studies, Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents, Antioxidant activity and inhibition of ultraviolet radiation-induced skin damage of Selenium-rich peptide fraction from selenium-rich yeast protein hydrolysate, Synthetic and medicinal chemistry of phthalazines: Recent developments, opportunities and challenges, Discovery of dipeptidyl peptidase 4 inhibitory peptides from Largemouth bass (Micropterus salmoides) by a comprehensive approach, Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular KCa1.1 channel stimulators, Identification of quinoline-chalcones and heterocyclic chalcone-appended quinolines as broad-spectrum pharmacological agents, Discovery of novel sulfonamide-containing aminophosphonate derivatives as selective COX-2 inhibitors and anti-tumor candidates, Inhibition of Aβ aggregates in Alzheimer’s disease by epigallocatechin and epicatechin-3-gallate from green tea, Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker, Synthesis and neuroprotective effects of novel chalcone-triazole hybrids, Batzelladine D and norbatzelladine L purified from marine sponge Monanchora arbuscula induce the reversal of fluconazole, Synthesis of some novel methyl β-orsellinate based 3, 5-disubstituted isoxazoles and their anti-proliferative activity: Identification of potent leads active against MCF-7 breast cancer cell, Synthesis and biological assessment of ciprofloxacin-derived 1,3,4-thiadiazoles as anticancer agents, Targeted potent antimicrobial benzochromene-based analogues: Synthesis, computational studies, and inhibitory effect against 14α-Demethylase and DNA Gyrase, Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance, New insight into enzymatic hydrolysis of peptides with site-specific amino acid d-isomerization, Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors, Design, synthesis, and biological evaluation of a novel indoleamine 2,3-dioxigenase 1 (IDO1) and thioredoxin reductase (TrxR) dual inhibitor, Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization, Dual active 1, 4-dihydropyridine derivatives: Design, green synthesis and in vitro anti-cancer and anti-oxidant studies, New cyanopyridine-based scaffold as PIM-1 inhibitors and apoptotic inducers: Synthesis and SARs study, Synthesis of substituted N-(2′-nitrophenyl)pyrrolidine-2-carboxamides towards the design of proline-rich antimicrobial peptide mimics to eliminate bacterial resistance to antibiotics, Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity, Flavonoid analogues as urease inhibitors: Synthesis, biological evaluation, molecular docking studies and in-silico ADME evaluation, Design and synthesis of novel tranilast analogs: Docking, antiproliferative evaluation and in-silico screening of TGFβR1 inhibitors, Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity, 2,4-Diketo esters: Crucial intermediates for drug discovery, Discovery of natural alkaloids as potent and selective inhibitors against human carboxylesterase 2, Design, synthesis and molecular modeling studies of 2-styrylquinazoline derivatives as EGFR inhibitors and apoptosis inducers, Toonaolides A–X, limonoids from Toona ciliata: Isolation, structural elucidation, and bioactivity against NLRP3 inflammasome, Antioxidant compounds from Banisteriopsis argyrophylla leaves as α-amylase, α-glucosidase, lipase, and glycation inhibitors, Asperochratides A–J, Ten new polyketides from the deep-sea-derived Aspergillus ochraceus, Design, synthesis and biological evaluation of novel 1,3,4-thiadiazole derivatives as anti-glioblastoma agents targeting the AKT pathway, Synthesis and controlled drug delivery studies of a novel Ubiquinol-Polyethylene glycol-Vitamin E adduct, Diterpenoids and triterpenoids from Triadica rotundifolia and their effects on microglial nitric oxide production, Download the ‘Understanding the Publishing Process’ PDF, Check the status of your submitted manuscript in the. Five Nobel Laureates Share Inspiration in Scientific Careers at Symposium in Tianjin University, Editorial Changes for Bioorganic Chemistry, Download the ‘Understanding the Publishing Process’ PDF, Check the status of your submitted manuscript in the.


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